SWATH-MS Based Proteomic Profiling of Prostate Cancer Cells Reveals Adaptive Molecular Mechanisms in Response to Anti-Androgen Therapy

SWATH-MS Based Proteomic Profiling of Prostate Cancer Cells Reveals Adaptive Molecular Mechanisms in Response to Anti-Androgen Therapy

Prostate cancer (PCa) is the second most common cancer affecting men worldwide. PCa shows a broad-spectrum heterogeneity in its biological and clinical behavior. Although androgen targeted therapy (ATT) has been the mainstay therapy for advanced PCa, it inevitably leads to treatment resistance and p...

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Bibliographic Details
Main Authors: Chamikara Liyanage, Adil Malik, Pevindu Abeysinghe, Judith Clements, Jyotsna Batra
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
prostate cancer
proteomics
transcriptomics
anti-androgen therapy
bicalutamide
enzalutamide
Online Access:https://www.mdpi.com/2072-6694/13/4/715

Internet

https://www.mdpi.com/2072-6694/13/4/715

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