Dualmarker: a flexible toolset for exploratory analysis of combinatorial dual biomarkers for clinical efficacy
Abstract Background An increasing number of clinical trials require biomarker-driven patient stratification, especially for revolutionary immune checkpoint blockade therapy. Due to the complicated interaction between a tumor and its microenvironment, single biomarkers, such as PDL1 protein level, tu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04050-6 |