Evaluation of the SpeeDx Carba (beta) multiplex real-time PCR assay for detection of NDM, KPC, OXA-48-like, IMP-4-like and VIM carbapenemase genes

Abstract Background Carbapenemase-producing organisms (CPOs) have emerged as antibiotic-resistant bacteria of global concern. Here we assessed the performance of the Carba (beta) assay, a multiplex real-time PCR assay developed by SpeeDx for the detection of key carbapenemase-encoding genes: KPC, ND...

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Bibliographic Details
Main Authors: Amanda Bordin, Ella Trembizki, Madeline Windsor, Rachel Wee, Lit Yeen Tan, Cameron Buckley, Melanie Syrmis, Haakon Bergh, Kyra Cottrell, Hosam M. Zowawi, Hanna E. Sidjabat, Patrick N. A. Harris, Graeme R. Nimmo, David L. Paterson, David M. Whiley
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Infectious Diseases
Subjects:
PCR
KPC
NDM
Online Access:http://link.springer.com/article/10.1186/s12879-019-4176-z