Down-regulation of calreticulin promotes apoptosis in hepatic stellate cells

Down-regulation of calreticulin promotes apoptosis in hepatic stellate cells

Objective To investigate the effect of calreticulin (CALR) down-regulation on apoptosis and endoplasmic reticulum stress (ERS) pathway in hepatic stellate cells (HSCs). Methods Small interfering RNA (siRNA) of CALR was transfected into HSC via liposome, and pro-fibrosis factor, namely transforming g...

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Bibliographic Details
Main Authors: DAI Linyu, YAN Yu, WANG Luguang, XIAO Yonghong
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
hepatic stellate cells
calreticulin
apoptosis
endoplasmic reticulum stress
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202012010.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/202012010.htm

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