Development of a sensitive outcome for economical drug screening for progressive multiple sclerosis treatment

Development of a sensitive outcome for economical drug screening for progressive multiple sclerosis treatment

Therapeutic advance in progressive multiple sclerosis (MS) has been very slow. Based on the transformative role magnetic resonance imaging (MRI) contrast-enhancing lesions had on drug development for relapsing-remitting MS, we consider the lack of sensitive outcomes to be the greatest barrier for de...

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Bibliographic Details
Main Authors: Peter Kosa, Danish Ghazali, Makoto Tanigawa, Chris Barbour, Irene Cortese, William Kelley, Blake Snyder, Joan Ohayon, Kaylan Fenton, Tanya Lehky, Tianxia Wu, Mark Greenwood, Govind Nair, Bibiana Bielekova
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Neurology
Subjects:
Multiple Sclerosis
clinical trials
quantitative MRI
outcome measures
Progressive multiple sclerosis
Composite scale
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00131/full

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http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00131/full

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