A Hybrid Framework for Simultaneous Process and Solvent Optimization of Continuous Anti-Solvent Crystallization with Distillation for Solvent Recycling
Anti-solvent crystallization is frequently applied in pharmaceutical processes for the separation and purification of intermediate compounds and active ingredients. The selection of optimal solvent types is important to improve the economic performance and sustainability of the process, but is chall...
Main Authors: | Jiayuan Wang, Lingyu Zhu, Richard Lakerveld |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
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Series: | Processes |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9717/8/1/63 |
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