Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Abstract Background Genetic studies in autism have pinpointed a heterogeneous group of loci and genes. Further, environment may be an additional factor conferring susceptibility to autism. Transcriptome studies investigate quantitative differences in gene expression between patient-derived tissues a...

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Bibliographic Details
Main Authors: Matthew Schwede, Shailender Nagpal, Michael J. Gandal, Neelroop N. Parikshak, Karoly Mirnics, Daniel H. Geschwind, Eric M. Morrow
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11689-018-9237-x