Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population

Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population

Single nucleotide polymorphisms (SNPs) in the IL1RL1–IL18R1 region are associated with various immune-mediated diseases. This study was carried out to investigate the causal variant for ocular Behçet’s disease (BD) and elucidate its target genes in the IL1RL1–IL18R1 region. Nine candidate functional...

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Bibliographic Details
Main Authors: Xiao Tan, Qingyun Zhou, Meng Lv, Handan Tan, Qingfeng Wang, Liming Zhang, Qingfeng Cao, Gangxiang Yuan, Guannan Su, Aize Kijlstra, Peizeng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Genetics
Subjects:
Behçet’s disease
uveitis
causal variant
bioinformatic analysis
functional study
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00645/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00645/full

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