Diastereodivergent chiral aldehyde catalysis for asymmetric 1,6-conjugated addition and Mannich reactions
Chiral aldehyde catalysis is a useful strategy in the catalytic asymmetric α-functionalization of amino methyl compounds but these reaction types are limited. Here, the authors report two chiral aldehyde-catalysed diastereodivergent reactions, namely, a 1,6-conjugate addition and a bio-inspired Mann...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19245-3 |