Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice

Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice

Mechanisms regulating the turnover of synaptic vesicle (SV) proteins are not well understood. They are thought to require poly-ubiquitination and degradation through proteasome, endo-lysosomal or autophagy-related pathways. Bassoon was shown to negatively regulate presynaptic autophagy in part by sc...

Full description

Bibliographic Details
Main Authors: Sheila Hoffmann-Conaway, Marisa M Brockmann, Katharina Schneider, Anil Annamneedi, Kazi Atikur Rahman, Christine Bruns, Kathrin Textoris-Taube, Thorsten Trimbuch, Karl-Heinz Smalla, Christian Rosenmund, Eckart D Gundelfinger, Craig Curtis Garner, Carolina Montenegro-Venegas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
bassoon
presynapse
autophagy
ubiquitination
E3 ubiquitin ligases
parkin
Online Access:https://elifesciences.org/articles/56590

Internet

https://elifesciences.org/articles/56590

Similar Items