RIPK1–RIPK3–MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils

RIPK1–RIPK3–MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils

Necroptosis is a pro-inflammatory cell death, which happens in the context of caspase-8 inhibition, allowing activation of the receptor interacting protein kinase 1–receptor interacting protein kinase 3–mixed lineage kinase domain-like (RIPK1–RIPK3–MLKL) axis. Recently, necroptosis has emerged as a...

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Bibliographic Details
Main Authors: Laiana A. Barbosa, Paloma P. Fiuza, Letícia J. Borges, Fellipe A. Rolim, Mayara B. Andrade, Nivea F. Luz, Graziele Quintela-Carvalho, Jonilson B. Lima, Roque P. Almeida, Francis K. Chan, Marcelo T. Bozza, Valeria M. Borges, Deboraci B. Prates
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
Leishmania infantum
neutrophils
necroptosis
cell death
RIPK3
mixed lineage kinase domain-like
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01818/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01818/full

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