The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients

Abstract Although metabolic syndrome (MetS) is linked to an elevated risk of cardiovascular disease (CVD), the cardiac-specific risk mechanism is unknown. Obesity, hypertension, and diabetes (all MetS components) are the most common form of CVD and represent risk factors for worse COVID-19 outcomes...

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Bibliographic Details
Main Authors: Olivia Ziegler, Nivedita Sriram, Vladimir Gelev, Denitsa Radeva, Kostadin Todorov, Jun Feng, Frank W. Selke, Simon C. Robson, Makoto Hiromura, Boian S. Alexandrov, Anny Usheva
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99143-w