Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation

Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation

Chronic graft-versus-host disease (cGvHD) is one of the major complications of allogeneic stem cell transplantation (HSCT). cGvHD is an autoimmune-like disorder affecting multiple organs and involves a dermatological rash, tissue inflammation and fibrosis. The incidence of cGvHD has been reported to...

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Bibliographic Details
Main Authors: Jukka Partanen, Kati Hyvärinen, Heike Bickeböller, Katarzyna Bogunia-Kubik, Rachel E. Crossland, Milena Ivanova, Francesca Perutelli, Ralf Dressel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
graft versus host disease (GvHD)
biomarkers
genetic screen
stem cell transplantation (HSCT)
gene marker
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.575492/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.575492/full

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