Immunosuppressive capacity of mesenchymal stem cells correlates with metabolic activity and can be enhanced by valproic acid

Immunosuppressive capacity of mesenchymal stem cells correlates with metabolic activity and can be enhanced by valproic acid

Abstract Background Mesenchymal stem cells (MSCs) have entered the clinic as an Advanced Therapy Medicinal Product and are currently evaluated in a wide range of studies for tissue regeneration or in autoimmune disorders. Various efforts have been made to standardize and optimize expansion and manuf...

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Bibliographic Details
Main Authors: Madeleine C. Killer, Philipp Nold, Katharina Henkenius, Lea Fritz, Tabea Riedlinger, Christina Barckhausen, Miriam Frech, Holger Hackstein, Andreas Neubauer, Cornelia Brendel
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Immunosuppression
T-cell
Cryopreservation
Valproic acid
Online Access:http://link.springer.com/article/10.1186/s13287-017-0553-y

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http://link.springer.com/article/10.1186/s13287-017-0553-y

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