Amelioration of Endoplasmic Reticulum Stress by Mesenchymal Stem Cells via Hepatocyte Growth Factor/c‐Met Signaling in Obesity‐Associated Kidney Injury

Amelioration of Endoplasmic Reticulum Stress by Mesenchymal Stem Cells via Hepatocyte Growth Factor/c‐Met Signaling in Obesity‐Associated Kidney Injury

Abstract Recent advances in the understanding of lipid metabolism suggest a critical role of endoplasmic reticulum (ER) stress in obesity‐induced kidney injury. Hepatocyte growth factor (HGF) is a pleiotropic cytokine frequently featured in stem cell therapy with distinct renotropic benefits. This s...

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Bibliographic Details
Main Authors: Bin Li, Joseph C. K. Leung, Loretta Y. Y. Chan, Wai Han Yiu, Ye Li, Sarah W. Y. Lok, Wing Han Liu, Kam Wa Chan, Hung Fat Tse, Kar Neng Lai, Sydney C. W. Tang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Stem Cells Translational Medicine
Subjects:
Induced pluripotent stem cells
Mesenchymal stem cells
Hepatocyte growth factor
Endoplasmic reticulum stress
Lipotoxicity
Online Access:https://doi.org/10.1002/sctm.18-0265

Internet

https://doi.org/10.1002/sctm.18-0265

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