A Phase I Comparative Pharmacokinetic and Safety Study of Two Intravenous Formulations of Vinorelbine in Patients With Advanced Non-Small Cell Lung Cancer

A Phase I Comparative Pharmacokinetic and Safety Study of Two Intravenous Formulations of Vinorelbine in Patients With Advanced Non-Small Cell Lung Cancer

Purpose: The aim of this study was to compare the pharmacokinetics and safety between two vinorelbine formulations [a new oil-in-water emulsion formulation (ANX) versus a previously marketed solution formulation (Navelbine)] in Chinese patients with advanced non-small cell lung cancer (NSCLC).Method...

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Bibliographic Details
Main Authors: Guolan Wu, Lihua Wu, Huili Zhou, Meihua Lin, Ling Peng, Yina Wang, You Zhai, Xingjiang Hu, Yunliang Zheng, Duo Lv, Jian Liu, Jianzhong Shentu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
pharmacokinetics
bioavailability
safety
vinorelbine
non-small-cell lung cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00774/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00774/full

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