A family pedigree of malignancies associated with BRCA1 pathogenic variants: a reflection of the state of art in China

Abstract Background Little is known about the status of genetic counseling for ovarian cancer in China. Case presentation We report a four-generation Chinese family with several types of cancer. The proband was a patient with high-grade serous ovarian cancer (HGSOC) who was found to harbor a pathoge...

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Bibliographic Details
Main Authors: Wenhui Li, Lei Li, Ming Wu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13053-019-0126-4