Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation.

The accessory gene regulator (agr) and staphylococcal accessory regulator (sarA) play opposing roles in Staphylococcus aureus biofilm formation. There is mounting evidence to suggest that these opposing roles are therapeutically relevant in that mutation of agr results in increased biofilm formation...

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Bibliographic Details
Main Authors: Karen E Beenken, Lara N Mrak, Linda M Griffin, Agnieszka K Zielinska, Lindsey N Shaw, Kelly C Rice, Alexander R Horswill, Kenneth W Bayles, Mark S Smeltzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2875390?pdf=render