IL-21: A Pleiotropic Cytokine with Potential Applications in Oncology

Interleukin- (IL-) 21 is a pleiotropic cytokine that regulates the activity of both innate and specific immunity. Indeed, it costimulates T and natural killer (NK) cell proliferation and function and regulates B cell survival and differentiation and the function of dendritic cells. In addition, IL-2...

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Bibliographic Details
Main Authors: Michela Croce, Valentina Rigo, Silvano Ferrini
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/696578