Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood

Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood

Abstract Background The synergistic effect of chemoradiation (CRT) has been previously demonstrated in several cancer types. Here, we investigated the systemic immune effects of CRT in patients with lung or head and neck cancer. Materials and methods Peripheral blood mononuclear cells were collected...

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Bibliographic Details
Main Authors: Jihane Boustani, Elodie Lauret Marie Joseph, Etienne Martin, Salim Benhmida, Benoit Lecoester, Florent Tochet, Céline Mirjolet, Cédric Chevalier, David Thibouw, Noémie Vulquin, Stéphanie Servagi, Xushan Sun, Olivier Adotévi
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Immunology
Subjects:
Chemoradiation
Immune suppressive cells
Tumor-specific T cell response
Online Access:https://doi.org/10.1186/s12865-021-00429-5

Internet

https://doi.org/10.1186/s12865-021-00429-5

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