Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection.

BACKGROUND/OBJECTIVE: Nicardipine is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. However, accumulating evidence suggests that inflammatory processe...

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Bibliographic Details
Main Authors: Bor-Ren Huang, Pei-Chun Chang, Wei-Lan Yeh, Chih-Hao Lee, Cheng-Fang Tsai, Chingju Lin, Hsiao-Yun Lin, Yu-Shu Liu, Caren Yu-Ju Wu, Pei-Ying Ko, Shiang-Suo Huang, Horng-Chaung Hsu, Dah-Yuu Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3951295?pdf=render