Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release

Abstract Miscarriage affects ~20% of pregnancies and maternal infections account for ~15% of early miscarriages. Chlamydia trachomatis (Ct) has been associated with miscarriage but the underlying mechanisms are unknown. Successful implantation requires endometrial stromal cell (ESC) decidualisation....

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Bibliographic Details
Main Authors: Sevi Giakoumelou, Nick Wheelhouse, Jeremy Brown, Jean Wade, Ioannis Simitsidellis, Douglas Gibson, Philippa T. K. Saunders, Patrick Horner, Gary Entrican, Sarah E. M. Howie, Andrew W. Horne
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02223-z