Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9.

Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9.

Epstein-Barr virus (EBV) causes a persistent infection in human B cells by establishing specific transcription programs to control B cell activation and differentiation. Transcriptional reprogramming of EBV infected B cells is predominantly driven by the action of EBV nuclear antigens, among them th...

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Bibliographic Details
Main Authors: Marie L Harth-Hertle, Barbara A Scholz, Florian Erhard, Laura V Glaser, Lars Dölken, Ralf Zimmer, Bettina Kempkes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3777872?pdf=render

Internet

http://europepmc.org/articles/PMC3777872?pdf=render

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