Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect

Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect

Apart from osteogenesis, neovascularization of the defect area is an important determinant for successful bone healing. Accordingly, several studies have employed the combined delivery of VEGFA and BMP2 for bone regeneration. Nevertheless, the outcomes of these studies are highly variable. The aim o...

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Bibliographic Details
Main Authors: Sunita Sharma, Ying Xue, Zhe Xing, Mohammed A. Yassin, Yang Sun, James B. Lorens, Anna Finne-Wistrand, Dipak Sapkota, Kamal Mustafa
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187219300117

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http://www.sciencedirect.com/science/article/pii/S2352187219300117

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