Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

Differentiating clinically between Parkinson's disease (PD) and the atypical parkinsonian syndromes of Progressive supranuclear palsy (PSP), corticobasal syndrome (CBS) and multiple system atrophy (MSA) is challenging but crucial for patient management and recruitment into clinical trials. Beca...

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Bibliographic Details
Main Authors: P.G. Foulds, O. Yokota, A. Thurston, Y. Davidson, Z. Ahmed, J. Holton, J.C. Thompson, H. Akiyama, T. Arai, M. Hasegawa, A. Gerhard, D. Allsop, D.M.A. Mann
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Dementia with Lewy Bodies
Multiple system atrophy
Alpha synuclein
Cerebrospinal fluid
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002579

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http://www.sciencedirect.com/science/article/pii/S0969996111002579

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