Folate-targeted PTEN/AKT/P53 signaling pathway promotes apoptosis in breast cancer cells

Objective Folate deficiency is closely related to the occurrence of human tumors and plays an important role in cell growth, differentiation, repair, and host defense. We studied the effects of folic acid on the apoptosis of breast cancer cells (MDA-MB-231) and on the activity of the PTEN/AKT/P53 si...

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Bibliographic Details
Main Authors: Wang Hexian, Fan Qiang, Zhang Longlong, Shi Danli, Wang Haibo, Wang Shoulian, Bian Bangjian
Format: Article
Language:English
Published: De Gruyter 2020-10-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pteridines-2020-0020