Synthesis of Hydrazone Derivatives of 4-[4-Formyl-3-(2-oxochromen-3-yl)pyrazol-1-yl]benzoic acid as Potent Growth Inhibitors of Antibiotic-resistant <i>Staphylococcus aureus</i> and <i>Acinetobacter baumannii</i>

Synthesis of Hydrazone Derivatives of 4-[4-Formyl-3-(2-oxochromen-3-yl)pyrazol-1-yl]benzoic acid as Potent Growth Inhibitors of Antibiotic-resistant <i>Staphylococcus aureus</i> and <i>Acinetobacter baumannii</i>

Microbial resistance to drugs is an unresolved global concern, which is present in every country. Developing new antibiotics is one of the guidelines of the Centers for Disease Control and Preventions (CDC) to combat bacterial resistance to drugs. Based on our lead molecules, we report the synthesis...

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Bibliographic Details
Main Authors: Jedidiah Whitt, Cameron Duke, Anthony Sumlin, Steven A. Chambers, Rawan Alnufaie, David Gilmore, Todd Fite, Alexei G. Basnakian, Mohammad A. Alam
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Coumarin
pyrazole
hydrazone
MRSA
drug-resistant
<i>Acinetobacter baumannii</i>
antimicrobials
ESKAPE pathogen
<i>Staphylococcus aureus</i>
Online Access:https://www.mdpi.com/1420-3049/24/11/2051

Internet

https://www.mdpi.com/1420-3049/24/11/2051

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