The therapeutic impact of human neonatal BMSC in a right ventricular pressure overload model in mice

The therapeutic impact of human neonatal BMSC in a right ventricular pressure overload model in mice

Abstract Objective To determine the impact of donor age on the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSCs) in treating adverse remodeling as the result of right ventricle (RV) pressure overload. Methods BMSCs were isolated from neonatal (< 1 month), infant (1 month to...

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Bibliographic Details
Main Authors: Rong Liufu, Guocheng Shi, Xiaomin He, Jingjing Lv, Wei Liu, Fang Zhu, Chen Wen, Zhongqun Zhu, Huiwen Chen
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow-derived mesenchymal stem cells
Right ventricular hypertrophy
Stem cell therapy
Vascular endothelial growth factor
Online Access:http://link.springer.com/article/10.1186/s13287-020-01593-y

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http://link.springer.com/article/10.1186/s13287-020-01593-y

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