Dicer regulates <it>Xist </it>promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

Dicer regulates <it>Xist </it>promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

<p>Abstract</p> <p>Background</p> <p>X chromosome inactivation is the mechanism used in mammals to achieve dosage compensation of X-linked genes in XX females relative to XY males. Chromosome silencing is triggered in <it>cis </it>by expression of the non-co...

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Bibliographic Details
Main Authors: Nesterova Tatyana B, Popova Bilyana C, Cobb Bradley S, Norton Sara, Senner Claire E, Tang Y Amy, Spruce Thomas, Rodriguez Tristan A, Sado Takashi, Merkenschlager Matthias, Brockdorff Neil
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/1/1/2

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http://www.epigeneticsandchromatin.com/content/1/1/2

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