Altered gating of Kv1.4 in the nucleus accumbens suppresses motivation for reward

Deficient motivation contributes to numerous psychiatric disorders, including withdrawal from drug use, depression, schizophrenia, and others. Nucleus accumbens (NAc) has been implicated in motivated behavior, but it remains unclear whether motivational drive is linked to discrete neurobiological me...

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Bibliographic Details
Main Authors: Bernadette O'Donovan, Adewale Adeluyi, Erin L Anderson, Robert D Cole, Jill R Turner, Pavel I Ortinski
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/47870