Biological and Clinical Changes in a Pediatric Series Treated with Off-Label JAK Inhibitors

Biological and Clinical Changes in a Pediatric Series Treated with Off-Label JAK Inhibitors

Off-label use of medications is still a common practice in pediatric rheumatology. JAK inhibitors are authorized in adults in the treatment of rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Although their use is not authorized yet in children, JAK inhibitors, based on their mechan...

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Bibliographic Details
Main Authors: Alessia Pin, Alessandra Tesser, Serena Pastore, Valentina Moressa, Erica Valencic, Anna Arbo, Alessandra Maestro, Alberto Tommasini, Andrea Taddio
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Janus kinase inhibitors
off-label medications
pediatric rheumatology
interferon signature
transcriptomics
juvenile idiopathic arthritis
Online Access:https://www.mdpi.com/1422-0067/21/20/7767

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https://www.mdpi.com/1422-0067/21/20/7767

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