Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR

Genetic variation in the genomic regulatory landscape likely plays a crucial role in the pathology of disease. Non-coding variants associated with disease can influence the expression of long intergenic non-coding RNAs (lincRNAs), which in turn function in the control of protein-coding gene expressi...

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Bibliographic Details
Main Authors: Megan Leask, Amy Dowdle, Hamish Salvesen, Ruth Topless, Tayaza Fadason, Wenhua Wei, William Schierding, Judith Marsman, Jisha Antony, Justin M. O’Sullivan, Tony R. Merriman, Julia A. Horsfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Genetics
Subjects:
enhancer
eQTL
gout
HNF4A
lincRNA
MAF
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00733/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00733/full

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