Supplementation of Diet With Different n-3/n-6 PUFA Ratios Ameliorates Autistic Behavior, Reduces Serotonin, and Improves Intestinal Barrier Impairments in a Valproic Acid Rat Model of Autism

Supplementation of Diet With Different n-3/n-6 PUFA Ratios Ameliorates Autistic Behavior, Reduces Serotonin, and Improves Intestinal Barrier Impairments in a Valproic Acid Rat Model of Autism

The implication of different dietary n-3/n-6 polyunsaturated fatty acids (PUFAs) ratios has been investigated in some neurodevelopmental disorders (including autism and depression). However, the mechanisms underlying the effects of different PUFAs ratios on the autism are still poorly understood. In...

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Bibliographic Details
Main Authors: Jinpeng Wang, Baihong Zheng, Dan Zhou, Jie Xing, Honghua Li, Jiayu Li, Zehui Zhang, Beilin Zhang, Ping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Psychiatry
Subjects:
polyunsaturated fatty acids
autism spectrum disorder
valproic acid
intestinal barrier
serotonin
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.552345/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2020.552345/full

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