The Pancreatic β-Cell: The Perfect Redox System

Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H<sub>2</sub>O<sub>2</sub> production for glucose-stimulated insulin secre...

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Bibliographic Details
Main Authors: Petr Ježek, Blanka Holendová, Martin Jabůrek, Jan Tauber, Andrea Dlasková, Lydie Plecitá-Hlavatá
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/2/197