Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Abstract Background Cancer-associated fibroblasts (CAFs) are believed to play an essential role in cancer initiation and development. However, little research has been undertaken to evaluate the role of CAFs in endometrial cancer (EC) progression. We aim to detect the functional contributions of CAF...

Full description

Bibliographic Details
Main Authors: Fei Teng, Wen-Yan Tian, Ying-Mei Wang, Yan-Fang Zhang, Fei Guo, Jing Zhao, Chao Gao, Feng-Xia Xue
Format: Article
Language:English
Published: BMC 2016-02-01
Series:Journal of Hematology & Oncology
Subjects:
Tumor microenvironment
Cancer-associated fibroblasts
Endometrial cancer
Stromal cell-derived factor-1α
CXCR4
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13045-015-0231-4

Internet

http://link.springer.com/article/10.1186/s13045-015-0231-4

Similar Items