6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents

Kinetoplastid parasites are the causative agents of Chagas disease (CD), leishmaniasis and human African trypanosomiasis (HAT). Despite a sustained decrease in the number of HAT cases, more efforts are needed to discover safe and effective therapies against CD and leishmaniasis. Kinetoplastid parasi...

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Bibliographic Details
Main Authors: Cai Lin, Fabian Hulpia, Izet Karalic, Laurens De Schepper, Louis Maes, Guy Caljon, Serge Van Calenbergh
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Nucleosides
Antikinetoplastid agents
Trypanosoma cruzi
Leishmania infantum
Trypanosoma brucei
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320721000373

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http://www.sciencedirect.com/science/article/pii/S2211320721000373

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