Case report: recurrent pituitary adenoma has increased load of somatic variants

Case report: recurrent pituitary adenoma has increased load of somatic variants

Abstract Background Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurren...

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Bibliographic Details
Main Authors: Raitis Peculis, Inga Balcere, Ilze Radovica-Spalvina, Ilze Konrade, Olivija Caune, Kaspars Megnis, Vita Rovite, Janis Stukens, Jurijs Nazarovs, Austra Breiksa, Aigars Kiecis, Ivars Silamikelis, Valdis Pirags, Janis Klovins
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Endocrine Disorders
Subjects:
Recurrent pituitary adenoma
NFPA
Pituitary adenoma exome sequencing
Tumour variant analysis
Online Access:https://doi.org/10.1186/s12902-020-0493-x

Internet

https://doi.org/10.1186/s12902-020-0493-x

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