OvHV-2 Glycoprotein B Delivered by a Recombinant BoHV-4 Is Immunogenic and Induces Partial Protection against Sheep-Associated Malignant Catarrhal Fever in a Rabbit Model

OvHV-2 Glycoprotein B Delivered by a Recombinant BoHV-4 Is Immunogenic and Induces Partial Protection against Sheep-Associated Malignant Catarrhal Fever in a Rabbit Model

An efficacious vaccine for sheep-associated malignant catarrhal fever (SA-MCF) is important for the livestock industry. Research towards SA-MCF vaccine development is hindered by the absence of culture systems to propagate the causative agent, ovine herpesvirus-2 (OvHV-2), which means its genome can...

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Bibliographic Details
Main Authors: Smriti Shringi, Donal O’Toole, Emily Cole, Katherine N. Baker, Stephen N. White, Gaetano Donofrio, Hong Li, Cristina W. Cunha
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Vaccines
Subjects:
viral-vectored vaccine
bovine herpesvirus-4
ovine herpesvirus-2
gammaherpesvirus
malignant catarrhal fever
rabbit model
Online Access:https://www.mdpi.com/2076-393X/9/2/90

Internet

https://www.mdpi.com/2076-393X/9/2/90

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