Novel data-driven, equation-free method captures spatio-temporal patterns of neurodegeneration in Parkinson's disease: Application of dynamic mode decomposition to PET

Most neurodegenerative disorders are characterized by progressive loss of neurons throughout the course of disease in the form of specific spatio-temporal patterns. To capture and quantify these coherent patterns across both space and time, traditionally one would either fit a pre-defined model with...

Full description

Bibliographic Details
Main Authors: Jessie Fanglu Fu, Ivan S. Klyuzhin, Martin J. McKeown, A. Jon Stoessl, Vesna Sossi
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219304966