Intestinal lesions are associated with altered intestinal microbiome and are more frequent in children and young adults with cystic fibrosis and cirrhosis.

BACKGROUND AND AIMS:Cirrhosis (CIR) occurs in 5-7% of cystic fibrosis (CF) patients. We hypothesized that alterations in intestinal function in CF contribute to the development of CIR. AIMS:Determine the frequency of macroscopic intestinal lesions, intestinal inflammation, intestinal permeability an...

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Bibliographic Details
Main Authors: Thomas Flass, Suhong Tong, Daniel N Frank, Brandie D Wagner, Charles E Robertson, Cassandra Vogel Kotter, Ronald J Sokol, Edith Zemanick, Frank Accurso, Edward J Hoffenberg, Michael R Narkewicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319904?pdf=render