NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue

NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue

Neurotrophin-3 (NT3), through activation of its tropomyosin-related kinase receptor C (TrkC), modulates neuronal survival and neural stem cell differentiation. It is widely distributed in peripheral tissues (especially vessels and pancreas) and this ubiquitous pattern suggests a role for NT3, outsid...

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Bibliographic Details
Main Authors: María Bové, Fermi Monto, Paloma Guillem-Llobat, M Dolores Ivorra, M Antonia Noguera, Andrea Zambrano, M Salome Sirerol-Piquer, Ana Cristina Requena, Mauricio García-Alonso, Teresa Tejerina, José T. Real, Isabel Fariñas, Pilar D’Ocon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
neurotrophin-3
tropomyosin-related kinase receptor C
beta-adrenoceptors
white adipose tissue
brown adipose tissue
adipocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.630097/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.630097/full

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