Inflammatory signatures for quick diagnosis of life-threatening infection during the CAR T-cell therapy

Inflammatory signatures for quick diagnosis of life-threatening infection during the CAR T-cell therapy

Abstract Background Chimeric antigen receptor-modified (CAR) T-cell immunotherapy is a novel promising therapy for treatment of B-cell malignancy. Cytokine release syndrome (CRS) and infection are the most common adverse events during CAR T-cell therapy. Similar clinical presentation of concurrent C...

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Bibliographic Details
Main Authors: Hui Luo, Na Wang, Liang Huang, Xiaoxi Zhou, Jin Jin, Chunrei Li, Di Wang, Bin Xu, Jinhuan Xu, Lijun Jiang, Jue Wang, Yang Cao, Yi Xiao, Qian Zhang, Xia Mao, Songya Liu, Liting Chen, Min Xiao, Jianfeng Zhou
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Chimeric antigen receptor-modified T-cell therapy
Infection
Cytokine release syndrome
Inflammatory factors
Online Access:http://link.springer.com/article/10.1186/s40425-019-0767-x

Internet

http://link.springer.com/article/10.1186/s40425-019-0767-x

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