Effects of statins on TH1 modulating cytokines in human subjects
Background. Activation of the innate immune system by cholesterol accelerates atherosclerosis. High levels or modified forms of cholesterol stimulate release of the inflammatory cytokines IL-12 and IL-18 that synergistically stimulate T lymphocytes to produce the atherogenic cytokine interferon-γ. W...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2015-02-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/764.pdf |