Effects of statins on TH1 modulating cytokines in human subjects

Background. Activation of the innate immune system by cholesterol accelerates atherosclerosis. High levels or modified forms of cholesterol stimulate release of the inflammatory cytokines IL-12 and IL-18 that synergistically stimulate T lymphocytes to produce the atherogenic cytokine interferon-γ. W...

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Bibliographic Details
Main Authors: Thomas R. Cimato, Beth A. Palka
Format: Article
Language:English
Published: PeerJ Inc. 2015-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/764.pdf