DUSP6 expression is associated with osteoporosis through the regulation of osteoclast differentiation via ERK2/Smad2 signaling

Abstract Osteoporosis-related fractures, such as femoral neck and vertebral fractures, are common in aged people, resulting in increased disability rate and health-care costs. Thus, it is of great importance to clarify the mechanism of osteoclast-related osteoporosis and find effective ways to avoid...

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Bibliographic Details
Main Authors: Boya Zhang, Putao Yuan, Guang Xu, Zhijun Chen, Zhifei Li, Huali Ye, Jiying Wang, Peihua Shi, Xuewu Sun
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04110-y