Effects of chronic prazosin, an alpha-1 adrenergic antagonist, on anxiety-like behavior and cortisol levels in a chronic unpredictable stress model in zebrafish (Danio rerio)

Post-traumatic stress disorder (PTSD) is often associated with significant neuroendocrine dysfunction and a variety of other symptoms. Today, there are limited efficacious treatment options for PTSD, none of which directly target the dysfunction observed with the hypothalamic-pituitary-adrenal (HPA)...

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Bibliographic Details
Main Authors: Michael P. O’Daniel, Maureen L. Petrunich-Rutherford
Format: Article
Language:English
Published: PeerJ Inc. 2020-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8472.pdf