Similarities and Differences in the Acute-Phase Response to SARS-CoV-2 in Rhesus Macaques and African Green Monkeys

Similarities and Differences in the Acute-Phase Response to SARS-CoV-2 in Rhesus Macaques and African Green Monkeys

Understanding SARS-CoV-2 immune pathology is critical for the development of effective vaccines and treatments. Here, we employed unbiased serial whole-blood transcriptome profiling by weighted gene network correlation analysis (WGCNA) at pre-specified timepoints of infection to understand SARS-CoV-...

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Bibliographic Details
Main Authors: Celeste Coleman, Lara A. Doyle-Meyers, Kasi E. Russell-Lodrigue, Nadia Golden, Breanna Threeton, Kejing Song, Genevieve Pierre, Carl Baribault, Rudolf P. Bohm, Nicholas J. Maness, Jay K. Kolls, Jay Rappaport, Joseph C. Mudd
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
COVID-19
systems biology
neutrophil (PMN)
interferon
African green monkey
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.754642/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.754642/full

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