Dapagliflozin Attenuates Hyperglycemia Related Osteoporosis in ZDF Rats by Alleviating Hypercalciuria

Recent studies showed that in patients with type 2 diabetes mellitus (T2DM), Sodium-dependent glucose transporters 2 inhibitor (SGLT2I) may cause potential adverse effects on skeleton such as increasing the risk of fracture. This risk is possibly mediated by effects induced by all SGLT2I class drugs...

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Bibliographic Details
Main Authors: Ji-Yu Wang, Yan-Zhen Cheng, Shuang-Li Yang, Min An, Hua Zhang, Hong Chen, Li Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00700/full