Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain.

18β-Glycyrrhetinic acid (GA) is the aglycone of glycyrrhizin that is a component of Glycyrrhiza, and has several pharmacological actions in the central nervous system. Recently, GA has been demonstrated to reach the brain by crossing the blood-brain barrier in rats after oral administration of a Gly...

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Bibliographic Details
Main Authors: Kazushige Mizoguchi, Hitomi Kanno, Yasushi Ikarashi, Yoshio Kase
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994142?pdf=render