Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium

Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium

Abstract Background Intra-synovial tendon injuries display poor healing, which often results in reduced functionality and pain. A lack of effective therapeutic options has led to experimental approaches to augment natural tendon repair with autologous mesenchymal stem cells (MSCs) although the effec...

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Bibliographic Details
Main Authors: Mohammad R. Khan, Jayesh Dudhia, Frederic H. David, Roberta De Godoy, Vedika. Mehra, Gillian Hughes, Stephanie G. Dakin, Andrew J. Carr, Allen E. Goodship, Roger K. W. Smith
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Intra-synovial tendon injury
Deep digital flexor tendon
Mesenchymal stem cells
Ovine
Magnetic iron-oxide nanoparticles
Online Access:http://link.springer.com/article/10.1186/s13287-018-0900-7

Internet

http://link.springer.com/article/10.1186/s13287-018-0900-7

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