A Muscle-Invasive Bladder Cancer Patient With High Tumor Mutational Burden and RB1 Mutation Achieved Bladder Preservation Following Chemotherapy Combined With Immunotherapy: A Case Report

A Muscle-Invasive Bladder Cancer Patient With High Tumor Mutational Burden and RB1 Mutation Achieved Bladder Preservation Following Chemotherapy Combined With Immunotherapy: A Case Report

Neoadjuvant chemotherapy followed by radical cystectomy is the standard of care for patients diagnosed with muscle-invasive bladder cancer (MIBC). However, urinary diversion following radical cystectomy significantly reduces patient quality of life. In addition, patients who significantly respond to...

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Bibliographic Details
Main Authors: Chuanzhen Cao, Zhichao Fu, Yueping Liu, Aiping Zhou, Jianfei Wang, Jianzhong Shou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
muscle-invasive bladder cancer
immunotherapy
chemotherapy
bladder-sparing
next-generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684879/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.684879/full

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